On Saturday, Chelsea will take on Newcastle United at Stamford Bridge while Arsenal will face Everton at the Emirates Stadium.
Sunderland will face Brighton at home, and West Ham United will host Manchester City on Saturday night.
Manchester United will welcome Aston Villa to Old Trafford on Sunday, and Liverpool will clash with Tottenham Hotspur at Anfield.
Stating his prediction, Merson told Sportskeeda that Burnley and Bournemouth will square with each other at 2-2.
Other predictions include:
Sunderland 2-2 Brighton & Hove Albion
Chelsea 3-1 Newcastle United
Arsenal 2-1 Everton
West Ham United 2-2 Manchester City
Crystal Palace 1-1 Leeds United
Manchester United 2-1 Aston Villa
Nottingham Forest 2-0 Fulham
Liverpool 3-0 Tottenham Hotspur
Brentford 2-1 Wolves
