Magoha died at Nairobi Hospital on Tuesday following a cardiac arrest.
He was reportedly rushed to the facility today after falling ill.
Prof Magoha was known as a tough-talking and no-nonsense CS during his time at the Education Ministry.
He leaves behind his wife Dr Magoha and son Dr Michael Magoha.
News of his death comes just days after Maseno University announced that he would be joining the institution as a professor of surgery at its School of Medicine.
“Yes it is true. He is no more,” his wife Dr Barbra confirmed as the professor passed on the same day that marks the International day of Education.
Before being appointed to cabinet five years ago, Prof George served as Vice-Chancellor at the University of Nairobi (UoN) for ten years (2005 to 2015). He also served as a Professor of Urological and Transplant Surgery at UoN’s College of Health Sciences. His medical career includes work and training in Nigeria, Ghana, Ireland and the United Kingdom. He also trained in Executive Management at Stanford University.
His death comes as he was set to attend his brother’s burial this weekend, condolences to the family.